fatty acid oxidation — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T9808	Tetradecylthioacetic acid		PPAR
	Tetradecylthioacetic acid is a synthetic fatty acid with a sulfur substitution in the β-position. This modification renders TTA unable to undergo complete β-oxidation and increases its biological activity, including acti...		PPAR
T10035	10,12-Tricosadiynoic acid	TDA,TCDA	Acyltransferase
	10,12-Tricosadiynoic acid is a highly selective and orally active inhibitor of acyl-CoA oxidase-1 (ACOX1). It can treat the high-fat diet- or obesity-induced metabolic diseases by improving mitochondrial lipid and ROS me...		Acyltransferase
T4535	Etomoxir sodium salt	(R)-Etomoxir sodium salt,Na salt,Etomoxir	Apoptosis , Others
	Etomoxir sodium salt ((R)-Etomoxir sodium salt) is a carnitine palmitoyltransferase 1a (CPT-1a) inhibitor that blocks fatty acid synthesis. Etomoxir sodium salt has antitumor activity.		Apoptosis , Others
T1889	CP-640186	CP 640186	Acetyl-CoA Carboxylase
	CP-640186 is an isozyme-nonselective Acetyl-CoA carboxylase (ACCase) inhibitor. The IC50s of CP-640186(CP 640186) is 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively.		Acetyl-CoA Carboxylase
T3622	CP-640186 hydrochloride	CP 640186 HCl	Acetyl-CoA Carboxylase
	CP-640186 hydrochloride (CP 640186 HCl) is an isozyme-nonselective acetyl-CoA carboxylase (ACC) inhibitor, including rat liver ACC1 (IC50: 53 nM) and rat skeletal muscle ACC2 (IC50: 61 nM); with higher metabolic stabilit...		Acetyl-CoA Carboxylase
T9768L	Ninerafaxstat trihydrochloride	Ninerafaxstat trihydrochloride(2254741-41-6 Free base)	Others
	Ninerafaxstat trihydrochloride shifts cellular metabolism to glucose oxidation from fatty acid oxidation. Ninerafaxstat trihydrochloride improves overall mitochondrial respiration and reduces fatty acid oxidation, thereb...		Others
T19663	Triheptanoin	UX 007,IND106011,UX007,UX-007,IND 106011,IND-106011	Others
	Triheptanoin (IND 106011) is a fatty acid metabolic modulator. It potentially for the treatment of fatty acid oxidation disorders and GLUT1.		Others
T12356	Palmitoylcarnitine	Palmitoyl DL-carnitine	Endogenous Metabolite
	Palmitoylcarnitine (Palmitoyl DL-carnitine) is a mitochondrial fatty acid oxidation intermediate that acts as a surfactant.		Endogenous Metabolite
T15157	Dodecanoylcarnitine	Lauroylcarnitine	Endogenous Metabolite
	Dodecanoylcarnitine ((-)-Lauroylcarnitine) has been associated with disturbances in fatty acid oxidation, and the use of Dodecanoylcarnitine resulted in an increase in the permeability of salmon calcitonin.		Endogenous Metabolite
T5246	Trans-2-butene-1,4-dicarboxylic acid	trans-2-Butene-1,4-dicarboxylic Acid,3-Hexenedioic Acid,trans-3-Hexenedioic Acid,β-Hydromuconic Acid	Others , Endogenous Metabolite
	Trans-2-butene-1,4-dicarboxylic acid (3-Hexenedioic Acid) is a normal human unsaturated dicarboxylic acid metabolite with increased excretion in patients with Dicarboxylic aciduria caused by fatty acid metabolism disorde...		Others , Endogenous Metabolite
TN2374	Methyl Linolenate	Linolenic acid methyl ester	Others
	Methyl Linolenate (Linolenic acid methyl ester) is a polyunsaturated fattly acid (PUFA). It is used in studies on the mechanisms and prevention of oxidation/peroxidation of unsaturated fatty acids.		Others
T21468	CVT-2738	UNII-NYS3I6283H,CVT 2738,EC 610-916-8,CVT2738,RS-94287	Others
	CVT-2738 (RS-94287) is a metabolite of Ranolazine. Ranolazine is a partial fatty acid oxidation (pFOX) inhibitor and anti-anginal drug.		Others
T5226	2-(2-Methylbenzamido)acetic acid	2-Methylhippuric acid,O-Toluric acid,N-(O-Toluoyl)glycine	Others , Endogenous Metabolite
	2-(2-Methylbenzamido)acetic acid (O-Toluric acid) is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. In certain cases, the measurement of these metabolites in body fluids can be used to diag...		Others , Endogenous Metabolite
T4944	Nervonic acid	cis-15-Tetracosenoic acid,Selacholeic acid	Endogenous Metabolite
	Nervonic acid (Selacholeic acid) is a long chain unsaturated fatty acid that is enriched in sphingomyelin. It consists of choline, sphingosine, phosphoric acid, and fatty acid. Nervonic acid may enhance the brain functio...		Endogenous Metabolite
T0846	L-Carnitine	L(-)-Carnitine,Levocarnitine	Endogenous Metabolite , Fatty Acid Synthase
	L-Carnitine (L(-)-Carnitine) is an amino acid derivative. L-Carnitine facilitates long-chain fatty acid entry into mitochondria, delivering substrate for oxidation and subsequent energy production. Fatty acids are utiliz...		Endogenous Metabolite , Fatty Acid Synthase
T13810	Palmitoylcarnitine chloride	Palmitoyl DL-carnitine chloride	PKC
	Palmitoylcarnitine chloride (Palmitoyl DL-carnitine chloride) is a mitochondrial fatty acid oxidation intermediate that mediates intralipid cardioprotection.Palmitoylcarnitine chloride eliminates colorectal cancer cell s...		PKC
T4734	Suberic acid	Octanedioic acid,1,8-Octanedioic acid	Others , Endogenous Metabolite
	Suberic acid (1,8-Octanedioic acid) is present in the urine of patients with fatty acid oxidation disorders. A metabolic breakdown product derived from oleic acid. Elevated levels of this unstaruated dicarboxylic acid ar...		Others , Endogenous Metabolite
T4535L	Etomoxir	(R)-(+)-Etomoxir	Antioxidant , CPT
	Etomoxir is a carnitine palmitoyltransferase 1a (CPT-1a) inhibitor that inhibits fatty acid oxidation by inhibiting CPT-1a and inhibits palmitate oxidation in humans, rats, and guinea pigs. Etomoxir has an inhibitory eff...		Antioxidant , CPT
T5245	N-Isovaleroylglycine	Isovaleroylglycine,N-Isovalerylglycine	Others , Endogenous Metabolite
	N-Isovaleroylglycine (Isovaleroylglycine) is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. However, the excretion of certain acyl glycines is increased in several inborn errors of metaboli...		Others , Endogenous Metabolite
T36831	9-Oxononanoic Acid	9-ONA	Phospholipase , CPT
	9-Oxononanoic Acid is an oxidized fatty acid, formed by the autoxidation of linoleic acid, which enhances phospholipase A2 (PLA2) activity and increases the production of thromboxane B2 in isolated human plasma.9-Oxonona...		Phospholipase , CPT